4-Cl-PVP Crystal: A Research Reference Overview

buy 4-cl-pvp crystal online|4-Chloro-α-pyrrolidinopentiophenone (4-Cl-PVP) is a halogenated synthetic cathinone belonging to the pyrrolidinophenone class, structurally related to α-PVP. At Foreverchems, we provide 4-Cl-PVP crystal exclusively as a qualified reference material for forensic analytical applications and laboratory research.

Chemical Profile

4-Cl-PVP is distinguished from α-PVP by the addition of a chlorine atom at the para position of the phenyl ring. Its IUPAC name is 1-(4-chlorophenyl)-2-(pyrrolidin-1-yl)pentan-1-one, with a molecular formula of C₁₅H₂₀ClNO for the free base (molecular weight approximately 265.8 g/mol) and C₁₅H₂₀ClNO·HCl for the hydrochloride salt . The hydrochloride salt exhibits a melting point of 207.4°C, a distinguishing physical characteristic useful for forensic identification .

The compound is presumed to act as a stimulant based on its structural similarity to α-PVP, though published pharmacological and toxicological data remain limited . A 2021 preclinical study published in Pharmacology Biochemistry and Behavior investigated the abuse potential of 4-Cl-α-PVP in rat models. The research demonstrated that 4-Cl-α-PVP produced reinforcing behaviors in self-administration assays and fully substituted for the discriminative-stimulus effects of methamphetamine, indicating abuse potential . The reinforcing potency of 4-Cl-α-PVP (0.094 mg/kg/infusion) was approximately one-third that of α-PVP (0.029 mg/kg/infusion) .

Analytical Characterization

The DEA Special Testing and Research Laboratory has published a validated analytical monograph for 4-Cl-α-PVP hydrochloride, including ¹H NMR, GC-MS retention time (11.208 min on HP-5 MS column), and EI mass spectrum, providing a verified spectral fingerprint for forensic identification . Certified reference solutions of 4-Cl-α-PVP hydrochloride are commercially available as 1 mg/mL methanol solutions suitable for GC/MS and LC/MS testing methods in clinical toxicology and forensic analysis .

Quality Standards at Foreverchems

Every batch of 4-Cl-PVP crystal undergoes comprehensive analytical verification. Our products are accompanied by certificates of analysis documenting purity levels, chemical identity, and relevant spectroscopic data. We maintain complete batch records for all reference materials, with HPLC and mass spectrometry data available for each lot.

Documentation and Compliance

Foreverchems provides certificates of analysis and technical documentation to support analytical and forensic research requirements. Our quality assurance framework includes standardized testing protocols and multi-stage verification processes.

Important Notice

4-Cl-α-PVP is a Schedule I controlled substance in the United States . It is controlled in Canada (Schedule I), Germany (NpSG), and the United Kingdom (Class B) . The compound was classified as a controlled substance by China’s Food and Drug Administration in 2018 . Researchers must verify their legal authority to handle such materials and comply with all applicable regulations in their location. Our products are supplied strictly for laboratory research and analytical reference purposes and are not intended for human consumption.