MDPHP Powder (Monkey Dust): A Research Reference Overview

monkey dust drug| 3,4-Methylenedioxy-α-pyrrolidinohexanophenone (MDPHP), commonly known by the street name “Monkey Dust,” is a synthetic cathinone belonging to the pyrovalerone class that has been associated with severe public health harms, particularly in the United Kingdom and Italy. At Foreverchems, we provide MDPHP powder exclusively as a qualified reference material for forensic analytical applications and laboratory research.

Chemical Profile

MDPHP is a higher homolog of MDPV, structurally characterized by an extended alkyl chain and a methylenedioxy substitution on the phenyl ring . Its molecular formula is C₁₇H₂₃NO₃ with a molecular weight of 289.37 g/mol and CAS number 776994-64-0 . The compound functions as a potent dopamine and norepinephrine reuptake inhibitor, with reported IC₅₀ values of 50 nM at the dopamine transporter (DAT) and 60 nM at the norepinephrine transporter (NET), while exhibiting substantially weaker activity at the serotonin transporter (SERT, IC₅₀ = 9,000 nM) . This DAT/SERT selectivity profile is characteristic of pyrovalerone-class cathinones and is associated with high abuse potential.

Research Context and Toxicological Findings

MDPHP was first reported to the European Union Drugs Agency’s Early Warning System by Sweden in November 2014 . In Finland, the substance has appeared in Customs Laboratory statistics since 2015, with nearly 3.4 kilograms seized in 2018 and approximately 10-15 samples annually after 2022 . The Finnish Medicines Agency has documented published reports of deaths associated with MDPHP use, including a case in Italy where a 48-year-old man died solely from MDPHP poisoning .

Clinical presentations from Swedish and German emergency department data include chest pain, breathing difficulties, anxiety, hypertension, aggression, psychosis, and hallucinations . A case series from Florence, Italy documented 45 MDPHP-involved intoxication cases between 2010 and 2023, with common features including tachycardia, agitation, and psychiatric symptoms .

Quality Standards at Foreverchems

Every batch of MDPHP powder undergoes comprehensive analytical verification. Our products are accompanied by certificates of analysis documenting purity levels, chemical identity, and relevant spectroscopic data. We maintain complete batch records for all reference materials, with HPLC and mass spectrometry data available for each lot.

Documentation and Compliance

Foreverchems provides certificates of analysis and technical documentation to support analytical and forensic research requirements. Our quality assurance framework includes standardized testing protocols and multi-stage verification processes.

Important Notice

MDPHP is controlled in numerous jurisdictions. In Finland, it is classified as a psychoactive substance prohibited on the consumer market under Government decree 1130/2014 . In the United Kingdom, it is a Class B controlled substance . It is specifically listed as a controlled substance in Japan and Hungary, and is controlled under analogue provisions in several other jurisdictions . Researchers must verify their legal authority to handle such materials and comply with all applicable regulations in their location. Our products are supplied strictly for laboratory research and analytical reference purposes and are not intended for human consumption.