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Introduction to 2-FDCK.

2-FDCK (2-Fluorodeschloroketamine, also known as 2-Fl-2′-Oxo-PCM or Fluoroketamine) is a synthetic dissociative compound belonging to the arylcyclohexylamine class . It is a structural analogue of the well-known anesthetic ketamine, distinguished by the substitution of the chlorine atom with a fluorine atom at the 2-position of the phenyl ring .

As a research chemical, 2-FDCK is primarily utilized in neuropharmacological studies investigating NMDA receptor antagonism, forensic analytical applications, and as a reference standard for identifying novel psychoactive substances . Its structural similarity to ketamine makes it a valuable tool for comparative studies on dissociative anesthetics.

At ForeverChems, we supply premium-grade 2-FDCK to researchers and professionals worldwide, with a focus on fast, discreet shipping across Europe.

Product Specifications

Product Name: 2-FDCK (2-Fluorodeschloroketamine)

CAS Number: 111982-49-1 (hydrochloride salt) 

Molecular Formula: C₁₃H₁₆FNO · HCl 

Molecular Weight: 257.73 g/mol 

Purity: ≥ 98% (verified by third-party HPLC testing) 

Form: Crystalline solid 

Storage: -20°C for long-term storage 

Availability: In stock, ready for immediate dispatch

Chemical Properties and Mechanism of Action

2-FDCK acts primarily as an NMDA receptor antagonist, a mechanism it shares with ketamine and other arylcyclohexylamines . This interaction with the NMDA receptor produces dissociative, anesthetic, and related effects in research models.

Key Pharmacological Data

NMDA Receptor Interaction: Research indicates that 2-FDCK induces conditioned place preference (CPP) and self-administration in animal models at doses comparable to ketamine . It dose-dependently substitutes for ketamine in drug discrimination tests, demonstrating its functional equivalence for abuse liability research .

Plasma Protein Binding: 2-FDCK exhibits a significantly higher unbound fraction (fu = 0.84) compared to ketamine (fu = 0.54), meaning a larger proportion of the compound is pharmacologically active in systemic circulation . This property makes 2-FDCK particularly useful for dose-response modeling studies.

Forensic Stability: 2-FDCK demonstrates exceptional stability in biological samples, with a mean recovery of 95.5% after 90 days of storage in urine at various temperatures . This robust stability simplifies sample handling and storage protocols in forensic toxicology applications.

Spectroscopic Properties: The compound exhibits characteristic UV absorption dominated by π-π* transitions, with a calculated energy gap of 5.65 eV between the highest occupied and lowest unoccupied molecular orbitals .

Why Choose ForeverChems?

1. Uncompromising Quality

We source our 2-FDCK from certified manufacturers with strict adherence to Good Manufacturing Practice (GMP) guidelines. Every batch undergoes independent HPLC and mass spectrometry testing to guarantee purity and potency.

2. Discreet and Secure Packaging

Your privacy is paramount. All orders are shipped in plain, unbranded packaging with no external markings indicating contents. Tamper-evident seals ensure security throughout transit.

3. Worldwide Shipping with European Focus

ForeverChems operates a robust global logistics network. We offer fast, reliable shipping to customers worldwide, with a particular emphasis on European markets:

• European Shipping: We have optimized shipping routes to ensure timely delivery to countries including Germany, France, the United Kingdom, Spain, Italy, the Netherlands, Switzerland, and more.

• Fast Transit Times: Typical delivery to European destinations ranges from 3 to 7 business days.

• Tracking Provided: Every order comes with a tracking number for real-time shipment monitoring.

4. Competitive Pricing and Bulk Discounts

We offer tiered pricing for bulk orders, making ForeverChems the cost-effective choice for large-scale research projects. Contact our sales team for custom quotes.

5. Responsive Customer Support

Our knowledgeable team is available to answer queries regarding product specifications, shipping, and order status. We prioritize clear and prompt communication.

Safety and Regulatory Information

2-FDCK is classified as a regulated substance in many jurisdictions. As of August 2024, it has been classified as a narcotic in France, prohibiting its production, sale, and use . The World Health Organization’s Expert Committee on Drug Dependence has recommended placing 2-FDCK on Schedule II of the 1971 Convention on Psychotropic Substances .

Important Considerations for Researchers:

• Controlled Status: 2-FDCK has been detected in 22 EU member states and is controlled in at least five member states . It is the customer’s responsibility to verify the legal status of this product in their jurisdiction before placing an order.

• Research Use Only: This product is intended for research, forensic, and analytical applications only. Not for human or veterinary use .

• Handling Precautions: Standard laboratory safety protocols should be followed when handling this compound. The material is harmful if swallowed, inhaled, or in contact with skin .

Shipping Information: Worldwide Delivery

ForeverChems is committed to making our products accessible globally. We ship to all major regions, including:

• Europe: All EU member states, UK, Switzerland, Norway, and more.

• North America: USA, Canada, Mexico.

• Asia: Japan, South Korea, Singapore, China, India, and others.

• Australia & Oceania

• South America

• Middle East & Africa

Shipping Methods:

• Standard Air Mail (7-21 days, tracking available)

• Express Courier (3-7 days, fully tracked, signature required)

Customs and Duties: Customers are responsible for any customs duties or import taxes applicable in their country. We provide all necessary documentation to facilitate smooth customs clearance.

How to Order

1. Browse Our Catalog: Select 2-FDCK and add to cart.

2. Checkout: Fill in your shipping details and choose your preferred payment method.

3. Payment: We accept cryptocurrencies and bank transfers for secure transactions.

4. Confirmation: Receive an order confirmation with tracking details upon dispatch.

Frequently Asked Questions

Q: What is 2-FDCK used for?

A: 2-FDCK is used as an analytical reference material for research and forensic applications, including NMDA receptor studies and drug testing .

Q: Is 2-FDCK legal to purchase?

A: 2-FDCK is a controlled substance in many countries, including several EU member states. It is the customer’s responsibility to verify the legal status of this product in their jurisdiction before placing an order .

Q: How should 2-FDCK be stored?

A: Store in a cool, dry place away from light and moisture. Long-term storage at -20°C is recommended for optimal stability .

Q: What if my order is seized by customs?

A: While we take every precaution to ensure successful delivery, we cannot guarantee customs clearance in all countries. Please refer to our shipping policy for more details.